What is IVF?
In vitro fertilisation (IVF) is one of several assisted reproductive techniques available to help people with fertility problems conceive.
During IVF, male and female gametes (eggs and sperm) are extracted and fertilised outside the body in a laboratory. The fertilised egg, now called an embryo, is then implanted back into the uterus to grow and develop.
The first known and successful IVF attempt took place in 1978 in the UK and was closely followed by other babies born using the same techniques. Jump forward to the present and IVF has become the most effective form of assisted reproductive technology with over 8 million people born as a result of this groundbreaking procedure.
Who would benefit from IVF?
IVF is a proven and effective option for:
– Families who are unable to achieve natural pregnancies
– Unexplained infertility.
– Women with blocked, damaged or missing fallopian tubes.
– Women who have undergone a tubal ligation.
– Men who have undergone a vasectomy.
– Patients with severe male infertility.
– Patients with a high risk of passing on hereditary genetic diseases (see PGT section).
– Patients with post cancer fertility treatment.
– Women who have cryopreserved eggs.
– Intended Parents who require the help of a gestational surrogate.
What is Egg Donation?
During a woman’s lifetime, many different factors can affect the ovaries, such as problems with ovulation, problems with the uterus, blocked fallopian tubes, early menopause, genetic diseases, and the effects of chemotherapy or radiotherapy and unfortunately all these factors can cause the ovaries to lose their capability of producing good quality eggs. Age is also an important factor. Women are born with all the eggs they will ever produce and as women age, the number of these eggs decreases because each month, unfertilised eggs are released from the body through the menstrual cycle. Once women reach their mid thirties, a drop in the number of eggs and an increase in the number of abnormal eggs may also be the reason for seeking the help of an egg donor.
Who would benefit from Egg Donation?
Oocyte donation can be used in both IVF and surrogacy programmes and could be a solution for:
– Women with polycystic ovarian reserve.
– Women with low ovarian reserve.
– Women with early menopause.
– Women who produce low-quality eggs or who do not respond well to hormonal treatment .
– When assisted reproduction treatments have failed on various occasions.
– Women that suffer from a genetic disease.
– When the access to the ovaries through a surgical procedure is complicated.
At Nest we have teamed leading fertility clinics and agencies around the world to offer a range of egg donation and IVF services.
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What is PGT?
Preimplantation Genetic Testing is a procedure used prior to the implantation of an embryo to detect and prevent the transmission of serious diseases caused by genetic and chromosomal alterations in embryos, to ensure that children born via IVF do not inherit these conditions.
How does it work?
PGS testing consists of an embryonic biopsy and screening this sample to ensure that all cells are euploid. When we talk about “euploid” and “aneuploid” we mean the number of pairs of chromosomes within an embryo. Healthy or euploid embryos should have 23 pairs of chromosomes, aneuploid embryos may have monosomy or trisomy which indicate a genetic condition. If the cells analysed are healthy, it is assumed that the embryo is also healthy and apt for implantation.
If you or your partner are known carriers of a specific genetic disorder, this can be determined by PGD testing (preimplantation genetic diagnosis) in which a geneticist will look for the exact condition.
Because PGT screening analyses chromosomes, the gender of the embryo is also revealed. In some countries, this is a completely legal practise.
Find out more about our services for IVF with Gender Selection.
Who would benefit from PGT?
Any couple undergoing in vitro fertilization is a potential candidate for aneuploidy testing and could benefit from performing genetic diagnosis tests, especially: Couples at risk of passing on a genetic disease or condition could also be candidates for PGD, in addition to the following groups:
– Patients with chromosomal disorders.
– Women aged 35 or over due to a higher percentage of abnormal eggs caused by age.
– Women who have experienced recurrent miscarriages .
– Women who have had more than one failed fertility treatment.
What is surrogacy?
Surrogacy is the act in which a third person agrees to carry and give birth to a baby for someone else. There are two different ways to make this happen:
Traditional Surrogacy, in which the surrogate agrees to provide her own eggs and pregnancy is achieved with artificial insemination or Gestational surrogacy, where the commissioning parents use their own gametes (or donor material) by means of IVF treatment and the surrogate – or in this case – the gestational carrier, does not have a biological link to the child she bears.
Surrogacy arrangements can be altruistic (meaning the surrogate only receives money to cover her expenses or loss of wages) or commercial, meaning the surrogate receives financial compensation.
When we talk about surrogacy on this page we are referring to Gestational commercial surrogacy agreements in countries with years of experience and in which there is a clear legal framework.
Who would benefit from Surrogacy?
– Couples who have struggled with infertility and who have exhausted other fertility options.
– Women who are unable to carry a pregnancy due to a medical reason.
– Women for who pregnancy would be a serious risk to their health.
– Same sex intended parents who want to have a genetic link to their baby .
– Single intended parents who are unable to opt for other fertility treatments.
Who can participate in Surrogacy programmes and where?
COUNTRY SURROGACY AN OPTION FOR REQUIREMENTS BIOLOGICAL LINK TO BABY PATERNITY & PASSPORT UKRAINE
Read more about Surrogacy in Ukraine here
Medical reason for surrogacy (female infertility and must meet certain criteria)Couples with a combined age under 110 At least one parent must have a biological link (this depends on nationality and laws in this country)Egg donors are usually Ukrainian phenotypes but other ethnic groups can be sourced. Sperm donors are local donors Both parents appear on the birth certificate as the surrogate has no legal rights under Ukrainian law. The baby typically inherits the nationality of the father and an application to the father’s embassy must be made to obtain travel documents or full passport before the baby can travel home. Wait times depend on each embassy. MEXICO
Read more about Surrogacy in Mexico here
Single Intended Parents (male & female)Heterosexual Married CouplesLGBTIUnmarried Couples None Intended Parents can opt for Sperm and/or egg donors and also adopt embryos for surrogacy programs. Mexico offers a wide range of different egg donor phenotypes. Paternity granted via a court decision. Baby obtains a Mexican passport and family can travel home within a month.